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17-(5-Substituted-2-thienyl) and 17-(5-substituted-2-thienylidene) derivatives of selected 17-oxo steroids Warren R. Biggerstaff, Nobuyuki Sugisaka, and Richard Albers pp 1 - 5; DOI: 10.1021/jm00301a001 |
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Steroidal cyclic ethers Paul Kurath and Raymond Oslapas pp 5 - 8; DOI: 10.1021/jm00301a002 |
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Synthesis and adrenocortical-inhibiting activity of substituted 2,2-diphenethylamines William A. Zuccarello, Benjamin Blank, Gertrude J. Frishmuth, Suzanne R. Cohen, Daniel Scaricaciottoli, and Franklin F. Owings pp 9 - 15; DOI: 10.1021/jm00301a003 |
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Use of a molecular orbital approach to the conformational analysis of glucopyranose W. Brock Neely pp 16 - 17; DOI: 10.1021/jm00301a004 |
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Electronic structure, antimalarial activity, and phototoxicity of selected quinolinemethanol derivatives and analogs William P. Purcell and K. Sundaram pp 18 - 21; DOI: 10.1021/jm00301a005 |
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Antimalarial activity of guanylhydrazone salts of aromatic ketones. I. Active substituent patterns Jefferson R. DoAmaral, Erwin J. Blanz, and Frederic A. French pp 21 - 25; DOI: 10.1021/jm00301a006 |
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N-Dialkylaminoalkylbiphenylamines as antimalarial and antischistosomal agents Warren G. Duncan and David W. Henry pp 25 - 29; DOI: 10.1021/jm00301a007 |
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Anthelmintic quaternary salts. III. Benzothiazolium salts David L. Garmaise, Gerard Y. Paris, Jacqueline Komlossy, C. H. Chambers, and R. C. McCrae pp 30 - 36; DOI: 10.1021/jm00301a008 |
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Catalysis by poly-L-lysine of aminolysis of penicillin by tris(hydroxymethyl)aminomethane Michael Averill Schwartz pp 36 - 38; DOI: 10.1021/jm00301a009 |
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Synthetic antibacterials. I. Nitrofurylvinyl-s-triazine derivatives Sadao Nishigaki, Fumio Yoneda, Hideko Matsumoto, and Keiko Morinaga pp 39 - 42; DOI: 10.1021/jm00301a010 |
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Imidazolecarboxyhydrazides. II. Chemistry and biological evaluation Jay Nematollahi and J. Rao Nulu pp 43 - 45; DOI: 10.1021/jm00301a011 |
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Compounds with potential enzyme inhibitory activity. Hydroxylamine analogs of 2-propynylamine David H. Moore, Joseph G. Cannon, William M. McIsaac, and Beng T. Ho pp 45 - 48; DOI: 10.1021/jm00301a012 |
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Diastereoisomers of formaldehyde derivatives of tetrahydrofolic acid and tetrahydroaminopterin Susan B. Horwitz, Gregory Kwok, Leslie Wilson, and Roy L. Kisliuk pp 49 - 51; DOI: 10.1021/jm00301a013 |
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Synthesis and anti-inflammatory activity of 2-aryl-2-.alpha.-piperidyl-1,3-dioxanes Paul Aeberli, William J. Houlihan, and Edward I. Takesue pp 51 - 54; DOI: 10.1021/jm00301a014 |
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Alkylation and acylation of B10H9NH3- K. C. John, Alexander Kaczmarczyk, and Albert H. Soloway pp 54 - 57; DOI: 10.1021/jm00301a015 |
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Pyridoxal phosphate. I. Phosphonic acid analogs of pyridoxal phosphate. Synthesis via Wittig reactions and enzymic evaluation Theodore L. Hullar pp 58 - 63; DOI: 10.1021/jm00301a016 |
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Structure-activity relations in the vitamin E series. II. Derivatives of .alpha.-tocopherol substituted at the 5-methyl group Wilfred A. Skinner, R. M. Parkhurst, Jean Scholler, and Klaus Schwarz pp 64 - 66; DOI: 10.1021/jm00301a017 |
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Irreversible enzyme inhibitors. CXXXIII. Differential irreversible inhibition of dihydrofolic reductase from three strains of L1210 leukemia, liver, spleen, and intestine of the mouse Bernard Randall Baker, Gerhardus J. Lourens, Rich B. Meyer, and Nicolaas M. J. Vermeulen pp 67 - 73; DOI: 10.1021/jm00301a018 |
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Irreversible enzyme inhibitors. CXXXIV. Effect of ring substitution on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-(m-fluorosulfonylphenylureido)phenoxymethyl]pyrimidine Bernard Randall Baker and Nicolaas Vermeulen pp 74 - 78; DOI: 10.1021/jm00301a019 |
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Irreversible enzyme inhibitors. CXXXV. Effect of ring substitution on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-(p-fluorosulfonylphenylureido)phenoxymethyl]pyrimidine Bernard Randall Baker and Nicolaas M. J. Vermeulen pp 79 - 81; DOI: 10.1021/jm00301a020 |
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Irreversible enzyme inhibitors. CXXXVI. 2,4-Diamino-5-(3,4-dichlorophenyl)-6-[p-(m-fluorosulfonylbenzamido)phenoxymethyl]pyrimidine, an active-site-directed irreversible inhibitor of dihydrofolic reductase. Effect of structure on isozyme specificity Bernard Randall Baker and Nicolaas M. J. Vermeulen pp 82 - 85; DOI: 10.1021/jm00301a021 |
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Irreversible enzyme inhibitors. CXXXVII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenoxymethyl)-2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine bearing a terminal sulfonyl fluoride Bernard Randall Baker and Nicolaas M. J. Vermeulen pp 86 - 88; DOI: 10.1021/jm00301a022 |
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Irreversible enzyme inhibitors. CXXXVIII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenethyl)-2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine with a terminal sulfonyl fluoride Bernard Randall Baker and Nicolaas M. J. Vermeulen pp 89 - 91; DOI: 10.1021/jm00301a023 |
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Irreversible enzyme inhibitors. CXXXIX. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)phenylpropionylsulfanilyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase. 6. Effects of substitution on the propionamide bridge on isozyme specificity Bernard Randall Baker and Gerhardus J. Lourens pp 92 - 94; DOI: 10.1021/jm00301a024 |
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Irreversible enzyme inhibitors. CXL. Active-site-directed irreversible inhibitors derived from 1-(3-chlorophenyl)-4,6-diamino-1,2-diydro-2,2-dimethyl-s-triazine Bernard Randall Baker and Gerhardus Lourens pp 95 - 101; DOI: 10.1021/jm00301a025 |
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Irreversible enzyme inhibitors. CXLI. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 1-[p-(p-fluorosulfonylphenylureidomethyl)phenyl]-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine Bernard Randall Baker and Gerhardus J. Lourens pp 101 - 104; DOI: 10.1021/jm00301a026 |
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Irreversible enzyme inhibitors. CXLII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-(p-aminophenoxypropyl)-2,4,6-triaminopyrimidine bearing a terminal sulfonyl fluoride Bernard Randall Baker and Rich B. Meyer pp 104 - 107; DOI: 10.1021/jm00301a027 |
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Irreversible enzyme inhibitors. CXLIII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-[3-(p-aminophenoxy)propyl]-2,4-diamino-6-methylpyrimidine with a terminal sulfonyl fluoride Bernard Randall Baker and Rich B. Meyer pp 108 - 111; DOI: 10.1021/jm00301a028 |
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Irreversible enzyme inhibitors. CXLIV. Proteolytic enzymes. 7. Additional active-site-directed irreversible inhibitors of trypsin derived from m- and p-(phenoxyalkoxy)benzamidines with a terminal sulfonyl fluoride Bernard Randall Baker and Edward H. Erickson pp 112 - 117; DOI: 10.1021/jm00301a029 |
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Irreversible enzyme inhibitors. CXLV. Proteolytic enzymes. 8. Active-site-directed irreversible inhibitors of .alpha.-chymotrypsin derived from .alpha.-(2-carboxy-4-chlorophenoxy)acetamide bearing a terminal sulfonyl fluoride Bernard Randall Baker and Jeffrey A. Hurlbut pp 118 - 122; DOI: 10.1021/jm00301a030 |
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Derivatives of imidazole. III. Synthesis and pharmacological activities of nitriles, amides, and carboxylic acid derivatives of imidazo[1,2-a]pyridine Luigi Almirante, Alfonso Mugnaini, Pierluigi Rugarli, Afro Gamba, Enzo Zefelippo, Nicola De Toma, and Walter Murmann pp 122 - 126; DOI: 10.1021/jm00301a031 |
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Spirans. XV. Spirans derived from 3-trifluoromethylcyclohexanone Leonard M. Rice, Bhagvandas S. Sheth, Kenneth R. Scott, and Charles F. Geschickter pp 126 - 130; DOI: 10.1021/jm00301a032 |
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Cholinergic receptor. II. Monosubstituted and bicyclic derivatives of cis-2-methyl-4-dimethylaminomethyl-1,3-dioxolane methiodide David R. Garrison, Marian May, H. F. Ridley, and David J. Triggle pp 130 - 134; DOI: 10.1021/jm00301a033 |
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Choline acetyltransferase inhibitors. Configurational and electronic features of styrylpyridine analogs Chester J. Cavallito, H. S. Yun, John Crispin Smith, and Francis F. Foldes pp 134 - 138; DOI: 10.1021/jm00301a034 |
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Role of alkyl substitution in 2,3-disubstituted and 3-substituted 4-quinazolones on the inhibition of pyruvic acid oxidation Surendra S. Parmar, K. Kishor, P. K. Seth, and R. C. Arora pp 138 - 141; DOI: 10.1021/jm00301a035 |
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Quinoxalines. XIV. Potential anticancer agents. Quinoxaline amino acid and dipeptide derivatives related to quinoxaline antibiotics Shlomo Gerchakov and Harry Pershing Schultz pp 141 - 144; DOI: 10.1021/jm00301a036 |
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Epimeric 2-hydroxy-2-phenylquinolizidines Joseph Sam, James D. England, and Davis Temple pp 144 - 146; DOI: 10.1021/jm00301a037 |
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Phosphorus analogs of nitrogenous drugs. II. 10H-Dibenzo[1,4]thiaphosphorins as central nervous system depressants Robert A. Wiley and Jerry H. Collins pp 146 - 149; DOI: 10.1021/jm00301a038 |
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Synthesis and biological properties of some dibenzazepines and dibenzazonines related to protostephanine Benjamin Pecherer, R. C. Sunbury, and Arnold Brossi pp 149 - 151; DOI: 10.1021/jm00301a039 |
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6-Oxa isosteres of uracil and thymine Robert E. Masingale, Sarah R. Bryant, Charles G. Skinner, James Nash, and Paul F. Kruse pp 152 - 154; DOI: 10.1021/jm00301a040 |
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Synthesis of carbonate analogs of dinucleosides. 3'-Thymidinyl 5'-thymidinyl carbonate, 3'-thymidinyl 5'-(5-fluoro-2'-deoxyuridinyl) carbonate, and 3'-(5-fluoro-2'-deoxyuridinyl) 5'-thymidinyl carbonate Mathias P. Mertes and Eugene A. Coats pp 154 - 157; DOI: 10.1021/jm00301a041 |
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Experimental tumor inhibitors. Antitumor activity of esters of .omega.-aryl-psi-nitro-psi-alken-1-ol and related compounds Kwang-Yuen Zee-Cheng and Chia-Chung Cheng pp 157 - 161; DOI: 10.1021/jm00301a042 |
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Potential anticancer agents. V. Aromatic nitrogen mustards related to 3-[N,N-bis(2-chloroethyl)amino]-4-methylbenzoic acid A. Cambanis, V. Dobre, and Ion Niculescu-Duvaz pp 161 - 164; DOI: 10.1021/jm00301a043 |
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Immunosuppressive activity of 2'-(3-dimethylaminopropylthio)cinnamanilide (cinanserin) and related compounds. IV John Krapcho, Robert C. Millonig, Chester F. Turk, and Blanche J. Amrein pp 164 - 166; DOI: 10.1021/jm00301a044 |
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Tumor inhibitors. XXXV. Myrsine saponin, the active principle of Myrsine africana S. Morris Kupchan, Pieter S. Steyn, Michael D. Grove, Stella M. Horsfield, and Sean W. Meitner pp 167 - 169; DOI: 10.1021/jm00301a045 |
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3-(Dialkylamino)methyladamantane-1-carboxylic acids Demetrios Kontonassios, Constantine Sandris, Georges Tsatsas, Silvano Casadio, Bruno Lumachi, and Carla Turba pp 170 - 172; DOI: 10.1021/jm00301a046 |
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Spirans. XVI. 9-Hydroxymethyl-3-azaspiro[5.5]undecanes Leonard M. Rice pp 172 - 173; DOI: 10.1021/jm00301a047 |
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Synthesis of 5-fluoro-2'-deoxyuridine-5'-carboxylic acid and its derivatives Kwan Chung Tsou, Norman J. Santora, and Elizabeth Eshelman Miller pp 173 - 175; DOI: 10.1021/jm00301a048 |
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Nucleoside analogs. Synthesis of 6-(6-amino-9-purinyl)-1,5-anhydro-6-deoxy-L-allitol Robert Vince and James Donovan pp 175 - 176; DOI: 10.1021/jm00301a049 |
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1-Acylindoles. IX. Synthesis of 1-cinnamoyl-5-methoxy-2-methyl-3-indolylaliphatic acids as potential anti-inflammatory agents Hisao Yamamoto and Masaru Nakao pp 176 - 178; DOI: 10.1021/jm00301a050 |
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Absolute configuration of some benzomorphan analgetics and related compounds Alan F. Casy and Anilkumar P. Parulkar pp 178 - 180; DOI: 10.1021/jm00301a051 |
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Racemic form of 5-ethyl-5-(3-hydroxy-1-methylbutyl)barbituric acid as a metabolite of pentobarbital Everett W. Maynert pp 180 - 181; DOI: 10.1021/jm00301a052 |
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Potential antimalarial agents. Derivatives of 2-chloro-1,4-naphthoquinone Benjamin Prescott pp 181 - 182; DOI: 10.1021/jm00301a053 |
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Synthesis of potential antineoplastic agents. XX. Compounds related to the 3-o-nitrophenylhydrazone of isatin Frank D. Popp pp 182 - 184; DOI: 10.1021/jm00301a054 |
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Quinoline antimalarials. Folded chloroquine Denis M. Bailey pp 184 - 185; DOI: 10.1021/jm00301a055 |
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Antimalarials related to 2-bromo-4,5-dimethoxy-N,N-bis(diethylaminoethyl)aniline Eugene L. Stogryn pp 185 - 187; DOI: 10.1021/jm00301a056 |
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Preparation of some sulfonamide and diaminodiphenyl sulfone analogs of 1,4-naphthoquinone F. Ivy Carroll, Kenneth H. Dudley, and H. Wayne Miller pp 187 - 189; DOI: 10.1021/jm00301a057 |
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Single crystal studies of chemotherapeutic agents. I. Structure of 1-(2-chloroethyl)-3-(5-carbamoylimidazol-4-yl)-.DELTA.2-1,2,3-triazolinium chloride Donald J. Abraham, John S. Rutherford, and Robert D. Rosenstein pp 189 - 190; DOI: 10.1021/jm00301a058 |
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3-Aza-A-homoandrostenes Arvin P. Shroff and C. H. Harper pp 190 - 191; DOI: 10.1021/jm00301a059 |
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Compounds related to insect juvenile hormone Nobel Wakabayashi pp 191 - 192; DOI: 10.1021/jm00301a060 |
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Analog of doisynolic acid. 3-Hydroxy-16,17-seco-16-norestra-1,3,5(10)-trien-17-oic acid Marley A. Bielefeld and Raymond Oslapas pp 192 - 195; DOI: 10.1021/jm00301a061 |
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Aziridinone derived from 1-aminoadamantane Erach R. Talaty and Aubry E. Dupuy pp 195 - 195; DOI: 10.1021/jm00301a062 |
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Aromatic fluorine compounds Jill M. Blunck, P. E. Hughes, and J. G. Scroggie pp 195 - 196; DOI: 10.1021/jm00301a063 |
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Synthesis of some antithyroid compounds. I Pramod K. Srivastava and Meerasahib Saleem pp 196 - 196; DOI: 10.1021/jm00301a064 |
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N-(.beta.-Guanidinoethyl)- and N-guanylazetidines Elvio Bellasio and Gianfranco Cristiani pp 196 - 197; DOI: 10.1021/jm00301a065 |
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Annual Reports in Medicinal Chemistry, 1967 Alfred Burger pp 198 - 198; DOI: 10.1021/jm00301a900 |
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Fortschritte der Chemie Organischer Naturstoffe Manuel Bernabe pp 198 - 198; DOI: 10.1021/jm00301a901 |
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The Problems and Prospects of LSD Alfred Burger pp 198 - 198; DOI: 10.1021/jm00301a902 |
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Potential antitumor agents. X. Bisquaternary salts Bruce F. Cain, G. J. Atwell, and Ralph N. Seelye pp 199 - 206; DOI: 10.1021/jm00302a001 |
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Demethylation studies. VI. Inhibition of hepatic microsomal oxygenation by .beta.-(2,4-dichloro-6-phenylphenoxy)ethylamine and related compounds Robert E. McMahon, Jack Mills, Hilman W. Culp, William R. Gibson, Warren M. Miller, and Frederick J. Marshall pp 207 - 211; DOI: 10.1021/jm00302a002 |
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Irreversible enzyme inhibitors. CXLVI. Active-site-directed irreversible inhibitors of xanthine oxidase derived from 9-(acylamidophenyl)guanines substituted with a terminal phenylenesulfonyl fluoride Bernard Randall Baker and William F. Wood pp 211 - 214; DOI: 10.1021/jm00302a003 |
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Irreversible enzyme inhibitors. CXLVII. Candidate active-site- directed irreversible inhibitors of xanthine oxidase derived from 9-(p-acylaminoalkoxyphenyl)guanines bearing a terminal sulfonyl fluoride Bernard Randall Baker and William F. Wood pp 214 - 216; DOI: 10.1021/jm00302a004 |
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Irreversible enzyme inhibitors. CXLVIII. Active-site-directed irreversible inhibitors of guanine deaminase derived from p-phenylguanine bearing a terminal phenylenesulfonyl fluoride Bernard Randall Baker and William F. Wood pp 216 - 220; DOI: 10.1021/jm00302a005 |
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Irreversible enzyme inhibitors. CL. Proteolytic enzymes. 9. (3,4-Dichlorophenoxyacetamido)pyridines bridged by a quaternary salt to a terminal phenylenesulfonyl fluoride. Potent irreversible inhibitors of .alpha.-chymotrypsin Bernard Randall Baker and Jeffrey A. Hurlbut pp 221 - 224; DOI: 10.1021/jm00302a006 |
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Irreversible enzyme inhibitors. CLI. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-(p-aminophenylbutyl)-2,4-diaminopyrimidines with a terminal phenylene sulfonyl fluoride Bernard Randall Baker and Rich B. Meyer pp 224 - 227; DOI: 10.1021/jm00302a007 |
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2,4-Diaminopyrimidines. Cyclization of 6-(phenacylthio) and related derivatives to thieno[2,3-d]pyrimidines and thiazolo[3,2-c]pyrimidines Barbara Roth pp 227 - 232; DOI: 10.1021/jm00302a008 |
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Tumor localizing agents. VII. Radioiodinated quinoline derivatives Raymond E. Counsell, P. Pocha, V. V. Ranade, J. Sterngold, and William H. Beierwaltes pp 232 - 236; DOI: 10.1021/jm00302a009 |
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S-[2-(.omega.-Aminoalkylamino)ethyl] dihydrogen phosphorothioates and related compounds as potential antiradiation agents James R. Piper, Carl R. Stringfellow, Robert D. Elliott, and Thomas Patrick Johnston pp 236 - 243; DOI: 10.1021/jm00302a010 |
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Terminally substituted S-[2(.omega.-aminoalkylamino)ethyl]dihydrogen phosphorothioates and related compounds as potential antiradiation agents James R. Piper, Carl R. Stringfellow, and Thomas Patrick Johnston pp 244 - 253; DOI: 10.1021/jm00302a011 |
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Synthesis of potential antiradiation agents from 3-substituted 2-oxazolidinones derived from phenol, benzenethiol, and related compounds Robert Daryl Elliott and Thomas Patrick Johnston pp 253 - 257; DOI: 10.1021/jm00302a012 |
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Aryl-substituted triazines with antidepressant activity Donald L. Trepanier, Kenneth L. Shriver, and John N. Eble pp 257 - 260; DOI: 10.1021/jm00302a013 |
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2,3-Benzoxazines. IX. Synthesis and central nervous system depressant activity of some 3,6- and 3,7-disubstituted 1H-3,4-dihydro-2,3-benzoxazines Giorgio Pifferi, Pietro Consonni, S. Banfi, and Alberto Diena pp 261 - 266; DOI: 10.1021/jm00302a014 |
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Absolute configurations of the pheniramines, methyl phenidates, and pipradrols Abbas Shafi'ee and Gilbert Hite pp 266 - 270; DOI: 10.1021/jm00302a015 |
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Synthesis and adrenocortical inhibiting activity of substituted diphenylalkylamines Benjamin Blank, William A. Zuccarello, Suzanne R. Cohen, Gertrude J. Frishmuth, and Daniel Scaricaciottoli pp 271 - 276; DOI: 10.1021/jm00302a016 |
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3-Amino-4-chromanone hydrochlorides and inhibition of gastric secretion D. Huckle, Ian M. Lockhart, and Michael Wright pp 277 - 279; DOI: 10.1021/jm00302a017 |
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Pyrazine diuretics. VI. (Pyrazinecarboxamido)guanidines Kenneth L. Shepard, James W. Mason, Otto W. Woltersdorf, James H. Jones, and Edward J. Cragoe pp 280 - 285; DOI: 10.1021/jm00302a018 |
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Pyrazine diuretics. VII. N-Amidino-3-substituted pyrazinecarboxamides James Holden Jones, Wilbur J. Holtz, and Edward J. Cragoe pp 285 - 287; DOI: 10.1021/jm00302a019 |
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Separation of morphinelike effects by optical resolution. Levo isomers as strong analgetics and narcotic antagonists J. Harrison Ager, Arthur E. Jacobson, and Everette I. May pp 288 - 289; DOI: 10.1021/jm00302a020 |
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Potential antihypertensive agents. III. 3,4-Dihydro-2H-1,4-benzothiazine derivatives Raj Nandan Prasad pp 290 - 294; DOI: 10.1021/jm00302a021 |
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Activity of phenothiazine anthelmintics as related to semiquinone formation Thomas N. Tozer, L. Dallas Tuck, and Craig John Cymerman pp 294 - 299; DOI: 10.1021/jm00302a022 |
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.alpha.,.alpha.,.alpha.,-Trifluorotoluamides as anticoccidial agents Dean E. Welch, Robert R. Baron, and Bruce A. Burton pp 299 - 303; DOI: 10.1021/jm00302a023 |
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Chemotherapeutic nitro-heterocycles. Derivatives of 5-nitrothiazole-2-carboxaldehyde and 5-nitrothiazole-2-carboxylic acid David W. Henry pp 303 - 306; DOI: 10.1021/jm00302a024 |
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Branched-chain sugar nucleosides. V. Synthesis and antiviral properties of several branched-chain sugar nucleosides Edward Walton, Susan R. Jenkins, Ruth F. Nutt, Frederick W. Holly, and Marjorie Nemes pp 306 - 309; DOI: 10.1021/jm00302a025 |
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Chemistry of cephalosporin antibiotics. XIII. Deacetoxycephalosporins. Synthesis of cephalexin and some analogs Charles W. Ryan, R. L. Simon, and Earle M. Van Heyningen pp 310 - 313; DOI: 10.1021/jm00302a026 |
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Analysis of biological linear free-energy relations Arthur Cammarata pp 314 - 317; DOI: 10.1021/jm00302a027 |
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2,6-Disubstituted phenylcyclopropylamines Alfred Burger, Jerome F. Siuda, Nathan Watzman, and Joseph P. Buckley pp 317 - 320; DOI: 10.1021/jm00302a028 |
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Cholinergic receptor. III. Parasympatholytic properties of cis- and trans-4-(dimethylaminomethyl)-2-phenyl-1,3-dioxolane methiodide Marian May, Horace F. Ridley, and David J. Triggle pp 320 - 321; DOI: 10.1021/jm00302a029 |
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Synthesis of o-methylnordehydrobufotenine, a new psychoactive indole Fred G. H. Lee, John W. Daly, and Albert A. Manian pp 321 - 322; DOI: 10.1021/jm00302a030 |
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2-Amino-3-phenyl-1,1,1-trifluoropropanes. Fluorine analogs of amphetamines Roger M. Pinder, Roger W. Brimblecombe, and David Morris Green pp 322 - 324; DOI: 10.1021/jm00302a031 |
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Synthesis of indole hydrazines as monoamine oxidase inhibitors K. Shanker, V. K. Agarwal, R. J. Selveraj, and Surendra S. Parmar pp 324 - 326; DOI: 10.1021/jm00302a032 |
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Synthesis and pharmacological properties of a series of 2-substituted aminomethyl-1,4-benzodioxanes Peter Nicholl Green, Maurice Shapero, and Catherine Wilson pp 326 - 329; DOI: 10.1021/jm00302a033 |
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Synthesis of 3,11.beta.,17.alpha.-trihydroxy-19-norpregna-1,3,5(10)-trien-20-one John S. Baran and Donna D. Langford pp 329 - 330; DOI: 10.1021/jm00302a034 |
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Barbiturates. Structural comparisons. I. Amobarbital, methylamobarbital, and butethal Balwant N. Dixit and Donald J. Abraham pp 330 - 332; DOI: 10.1021/jm00302a035 |
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Structure-activity relations of ethylenimines. VIII. Optically active methyl-substituted ethylenimines Albert T. Bottini, Vasu Dev, Barry F. Dowden, and Allen J. Gandolfi pp 332 - 333; DOI: 10.1021/jm00302a036 |
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Syntheses of 8-bromo-5'-adenylate-containing nucleotides Donald B. McCormick and George E. Opar pp 333 - 334; DOI: 10.1021/jm00302a037 |
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Synthesis of potential antineoplastic agents. Substituted phenylcyclohexenes Sue K. Core and Frederick J. Lotspeich pp 334 - 336; DOI: 10.1021/jm00302a038 |
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Antimalarial compounds. X. Biguanide and amidinourea derivatives of diphenyl sulfide, sulfoxide, and sulfone Barbara Serafin, Tadeusz Urbanski, and D. C. Warhurst pp 336 - 337; DOI: 10.1021/jm00302a039 |
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Catalytic hydrogenolysis of benzylmethylamino analogs of methadone and .alpha.-methadol Alan F. Casy, M. M. A. Hassan, and Fac. Pharm. pp 337 - 339; DOI: 10.1021/jm00302a040 |
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Synthesis of some ureidodihydrofurans and related pyrimidones as potential antimalarials Ernest Campaigne, Richard L. Ellis, M. Bradford, and J. Ho pp 339 - 342; DOI: 10.1021/jm00302a041 |
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.omega.-Dithiolanyl amino acids Mathias P. Mertes and Arthur A. Ramsey pp 342 - 343; DOI: 10.1021/jm00302a042 |
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Antimicrobial activity of a series of aminoalkyl esters of benzyldithiocarbamic acids Robert C. Tweit, Robert D. Muir, and Seth Mizuba pp 343 - 346; DOI: 10.1021/jm00302a043 |
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3-Alkoxyestra-1,3,5(10)-trien-17.beta.-ols David J. Triggle, Horace F. Ridley, and D. M. DeMaio pp 346 - 346; DOI: 10.1021/jm00302a044 |
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Synthesis of DL-2-(2,4,6-Cycloheptatrien-1-yl)glycine Stephen Hanessian and Guenther Schueltze pp 347 - 347; DOI: 10.1021/jm00302a045 |
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3-Fluoropropane-1,2-diol from glycidol (hydroxymethyloxirane) Robert J. Dummel and Ernest Kun pp 347 - 347; DOI: 10.1021/jm00302a046 |
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Synthesis of 2-hydroxy-p-phenetidine and derivatives Moses J. Namkung and T. Lloyd Fletcher pp 348 - 348; DOI: 10.1021/jm00302a047 |
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Correlation of biological activity with chemical structure. Use of molar attraction constants James A. Ostrenga pp 349 - 352; DOI: 10.1021/jm00303a001 |
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Mathematical approach to structure-activity study of sympathomimetic amines. Norepinephrine uptake inhibition Takashi Ban and Toshio Fujita pp 353 - 356; DOI: 10.1021/jm00303a002 |
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Repository drugs. IV. 4',4'''-Sulfonylbisacetanilide (acedapsone, DADDS) and related sulfanilylanilides with prolonged antimalarial and antileprotic action Edward F. Elslager, Zoe B. Gavrilis, Annette A. Phillips, and Donald F. Worth pp 357 - 363; DOI: 10.1021/jm00303a003 |
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Repository drugs. V. 4',4'''-[p-Phenylenebis(methylidyneimino-p-phenylenesulfonyl)]bisacetanilide (PSBA) and related 4',4'''-[bis(imino-p-phenylenesulfonyl)]bisanilides; a novel class of long-acting antimalarial and antileprotic agents Edward F. Elslager, Annette A. Phillips, and Donald F. Worth pp 363 - 367; DOI: 10.1021/jm00303a004 |
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Antimalarials. Unsaturation in the chloroquine side chain and antimalarial activity Tara Singh, Robert G. Stein, and John H. Biel pp 368 - 371; DOI: 10.1021/jm00303a005 |
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3,5-Dinitrosalicylic acid (5-nitrofurfurylidene)hydrazide, a potent preventive of histomoniasis in turkeys E. W. Berndt, H. Van Essen, B. G. Held, and R. D. Vatne pp 371 - 374; DOI: 10.1021/jm00303a006 |
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Nitroheterocyclic antimicrobial agents. I. Nitrothiazolecarboxaldehyde derivatives Goro Asato, Gerald Berkelhammer, and Edward L. Moon pp 374 - 379; DOI: 10.1021/jm00303a007 |
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Synthesis of 3-(5-nitrofurfurylideneamino)hydantoins and N-(ethoxycarbonyl)amino acid nitrofurfurylidenehydrazides George Carlin Wright, Julian G. Michels, and Claude F. Spencer pp 379 - 381; DOI: 10.1021/jm00303a008 |
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1,2,4-Oxadiazolylpyridinium salts. Oral hypoglycemic agents William J. Fanshawe, Victor J. Bauer, S. R. Safir, D. A. Blickens, and S. J. Riggi pp 381 - 383; DOI: 10.1021/jm00303a009 |
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Synthesis and diuretic properties of some N-alkylaminocarbonyl- and N-pyrrolylcarbonylanthranilic acid derivatives Arthur M. Felix, Leo B. Czyzewski, Donald P. Winter, and R. Ian Fryer pp 384 - 387; DOI: 10.1021/jm00303a010 |
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A-Nor-5.alpha.-androstane derivatives. IV. Structures with potential antiimplantation activity Marguerite Minssen-Guette, Jean Jacques, Rosemarie Rettenmaier, F. S. Waksmunski, David B. R. Johnston, and Thomas B. Windholz pp 388 - 393; DOI: 10.1021/jm00303a011 |
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Antiandrogenic and progestational activity of some 17-oxygenated 15-dehydro steroids T. L. Popper, J. N. Gardner, R. Neri, and H. L. Herzog pp 393 - 396; DOI: 10.1021/jm00303a012 |
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Preparation and antiinflammatory properties of some 1-substituted 3-(5-tetrazolylmethyl)indoles and homologs Peter F. Juby and T. W. Hudyma pp 396 - 401; DOI: 10.1021/jm00303a013 |
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Benzo[g]quinolines. I. Synthesis and pharmacological evaluation of cis- and trans-1-alkyl-5,5-dimethyl-1,2,3,4a,5,10,10a-octahydrobenzo[g]quinolin-7-ol. A class of narcotic antagonists William F. Michne and N. F. Albertson pp 402 - 405; DOI: 10.1021/jm00303a014 |
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Synthesis of 6,7-benzomorphan and related nonquaternary carbon structures with marked analgetic activity Ken Kanematsu, Mikio Takeda, Arthur E. Jacobson, and Everette L. May pp 405 - 408; DOI: 10.1021/jm00303a015 |
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Irreversible enzyme inhibitors. CLII. Proteolytic enzymes. 10. Inhibition of guinea pig complement by substituted benzamidines Bernard Randall Baker and Edward H. Erickson pp 408 - 414; DOI: 10.1021/jm00303a016 |
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Irreversible enzyme inhibitors. CLIII. Proteolytic enzymes. 11. Inhibition of guinea pig complement by substituted phenoxyacetamides Bernard Randall Baker and Jeffrey A. Hurlbut pp 415 - 419; DOI: 10.1021/jm00303a017 |
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Pyridoxal phosphate. II. Benzene analogs. 2-Formylphenoxyacetic acids as potential antimetabolites of pyridoxal phosphate Theodore L. Hullar and D. L. Failla pp 420 - 424; DOI: 10.1021/jm00303a018 |
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Pyridoxal phosphate. III. Pyrimidine analogs. 3-(Substituted 5-pyrimidyl)propionic acids as potential inhibitory analogs of pyridoxal phosphate Theodore L. Hullar and W. C. French pp 424 - 426; DOI: 10.1021/jm00303a019 |
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Conformational aspects of carbamates in the inhibition of the Hill reaction Marvin R. Boots pp 426 - 428; DOI: 10.1021/jm00303a020 |
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Conformational study of .beta.-phenethanolamine receptor sites. II. Syntheses of the dl-3-phenyl-3-hydroxy-trans-decahydroquinolines Edward E. Smissman and Gary S. Chappell pp 429 - 432; DOI: 10.1021/jm00303a021 |
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Conformational study of acetylcholine receptor sites. II. Syntheses of the dl-1-methyl-3-acetoxy-trans-decahydroquinoline methiodides Edward E. Smissman and Gary S. Chappell pp 432 - 435; DOI: 10.1021/jm00303a022 |
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Aroylakylpyrrolidines. Central nervous system depressants William J. Welstead, Grover C. Helsley, Robert L. Duncan, Albert D. Cale, C. Roy Taylor, John P. DaVanzo, Bernard V. Franko, and Carl D. Lunsford pp 435 - 441; DOI: 10.1021/jm00303a023 |
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Synthesis and biological properties of some 1-substituted 3-(o-methoxyphenoxy)pyrrolidines Robert L. Duncan, Grover C. Helsley, William J. Welstead, and Bernard V. Franko pp 442 - 444; DOI: 10.1021/jm00303a024 |
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Dibenz[c,d,h]azulenes. II. Bridged amitriptyline analogs Eugene Galantay, Clarence Hoffman, Nicholas Paolella, John Gogerty, Louis Iorio, George Leslie, and J. H. Trapold pp 444 - 449; DOI: 10.1021/jm00303a025 |
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Pharmacologically active acetylene compounds. II. Propynyl-substituted indole derivatives John L. Neumeyer, Urve V. Moyer, and Jack E. Leonard pp 450 - 452; DOI: 10.1021/jm00303a026 |
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.beta.-Adrenergic blocking agents. IV. Variation of the 2-naphthyl group of pronethalol [2-isopropylamino-1-(2-naphthyl)ethanol] Ralph Howe, Bernard J. McLoughlin, Balbir S. Rao, Leslie Harold Smith, and M. S. Chodnekar pp 452 - 458; DOI: 10.1021/jm00303a027 |
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Synthesis of 2,4,5-trihydroxyphenylalanine (6-hydroxydopa). A centrally active norepinephrine-depleting agent Helen H. Ong, Cyrus R. Creveling, and John W. Daly pp 458 - 461; DOI: 10.1021/jm00303a028 |
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Carbamate derivatives related to meprobamate Bernard J. Ludwig, Leo S. Powell, and Frank Milan Berger pp 462 - 472; DOI: 10.1021/jm00303a029 |
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1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity Asher Kalir, Habib Edery, Zvi Pelah, D. Balderman, and Gila Porath pp 473 - 477; DOI: 10.1021/jm00303a030 |
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Spasmolytics. I. 3-Tropanyl 2-arylacrylates and 3-tropanyl 2-arylhydracrylates Henry C. Caldwell, Joseph A. Finkelstein, Dordge Arbakov, Carol Pelikan, and William G. Groves pp 477 - 480; DOI: 10.1021/jm00303a031 |
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Arundo donax. Phytochemical and pharmacological evaluation Shibnath Ghosal, Shibnath K. Dutta, Ajit K. Sanyal, and S. K. Bhattacharya pp 480 - 483; DOI: 10.1021/jm00303a032 |
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Potential Antiradiation Agents. I. Primary Aminoalkanethiosulfuric Acids Daniel L. Klayman, Marie M. Grenan, and David P. Jacobus pp 510 - 512; DOI: 10.1021/jm00303a600 |
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The Reaction of Benzylpenicillemic Acid with Thiol-Containing Compounds. The Formation of a Possible Penicillin Antigenic Determinant Eugene S. Wagner, William W. Davis, and Marvin Gorman pp 483 - 487; DOI: 10.1021/jm00303a601 |
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Centrally Acting Emetics. III. Derivatives of beta-Naphthylamine William K. Sprenger, Joseph G. Cannon, B. K. Bahman, and Allan M.Burkman pp 487 - 490; DOI: 10.1021/jm00303a602 |
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Synthesis and Evaluation of Esters of N, N-Bis(2-chloroethyl)-p-aminophenol and N,N-Bis(2-bromoethyl)-p-aminophenol as Potential Antitumor Agents S. Vickers, P. Hebborn, J. F. Moran, and D. J. Triggle pp 491 - 494; DOI: 10.1021/jm00303a603 |
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2-Chloroadenosine 5'-Phosphate and 2-Chloroadenosine 5'-Diphosphate, Parmacologically Active Nucleotide Analogs G. Gough, M. Helen Maguire, and Frank Michal pp 494 - 498; DOI: 10.1021/jm00303a604 |
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Nucleosides of 2-Fluoroadenine John A. Montgomery, and Kathleen Hewson pp 498 - 504; DOI: 10.1021/jm00303a605 |
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Potential Antileukemic and Immunosuppressive Drugs. II. Further Studies with Benzo-2,1,3-oxadiazoles (Benzofurazans) and Their N-Oxides (Benzofuroxans) P. B. Ghosh, and M. W. Whitehouse pp 505 - 507; DOI: 10.1021/jm00303a606 |
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[3-(2-Mercaptoethylamino)propyl]oxamide and Related Compounds as Potential Antiradiation Agents Robert D. Elliott, and Thomas P. Johnston pp 507 - 509; DOI: 10.1021/jm00303a607 |
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Compounds Affecting the Central Nervous System. V. Substituted 3-Dialkylaminoalkylindenes P. M. G. Bavin, C. R. Ganellin, J. M. Loynes, and R. G. W. Spickett pp 513 - 516; DOI: 10.1021/jm00303a608 |
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Synthesis and Relative Urinary Excretion Rates of the Enantiomers of Warfarin-4-14C and Phenprocoumon-2-14C L. A. Goding, and B. D. West pp 517 - 518; DOI: 10.1021/jm00303a609 |
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Notes. Antimalarial and Antischistosomal Agents. N, N''-[Sulfonylbis(p-phenyleneazo-1,4-napthylene)]bis(N,N'-dialkylakylenediamines) Edward F. Elslager, and Annette A. Phillips pp 519 - 521; DOI: 10.1021/jm00303a610 |
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Notes. 2-(Alkyl- and Arylamino)-5-nitrothiazole Derivatives with Antiamebic, Antitrichomonal, and Antimalarial Properties Leslie M. Werbel, Edward F. Elslager, Annette A. Phillips, Donald F. Worth, Peter J. Islip, and M. C. Neville pp 521 - 524; DOI: 10.1021/jm00303a611 |
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Notes. Antimalarials. Some Quinuclidine Derivatives of 7-Chloro-4-aminoquinoline and 6-Methoxy-8-aminoquinoline Tara Singh, Robert G. Stein, Harlen H. Koelling, John F. Hoops, and John H. Biel pp 524 - 526; DOI: 10.1021/jm00303a612 |
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Notes. Some New Thiosemicarbazides, Thioureas, and Thiosemicarbazones from 4-Isothiocyanatobenzenesulfonpiperidide D. M. Wiles, and T. Suprunchuk pp 526 - 527; DOI: 10.1021/jm00303a613 |
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Notes. Synthetic Penicillins Derived from Cycloheptatrienecarboxylic Acids Stephen Hanessian, and Günther Schütze pp 527 - 529; DOI: 10.1021/jm00303a614 |
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Notes. Synthetic Penicillins Derived from Benznorcaradienecarboxylic Acids Stephen Hanessian, and Günther Schütze pp 529 - 531; DOI: 10.1021/jm00303a615 |
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Notes. Researches in the Field of Antiviral Compounds. Mannich Bases of 3-Hydroxycoumarin Gian M. Cingolani, Fulvio Gualtieri, and Maria Pigini pp 531 - 532; DOI: 10.1021/jm00303a616 |
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Notes. A Nonmutagenic Thymidine Analog with Antiviral Activity. 5-Ethyldeoxyuridine M. Swierkowski, and D. Shugar pp 533 - 534; DOI: 10.1021/jm00303a617 |
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Notes. 4,4',6,6'-Tetrabromo-2,2'-biphneyldiol Mono(dihydrogen phosphate). A New Agent for Combating Distomatosis S. van der Meer, and H. Pouwels pp 534 - 535; DOI: 10.1021/jm00303a618 |
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Notes. Nitrofuryl Heterocycles. VIII. 2-(5-Nitro-2-furyl)cinchoninic Acid Derivatives Homer A. Burch pp 535 - 536; DOI: 10.1021/jm00303a619 |
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Notes. Potential Antimalarials. Some Novel α-(Disubstituted Aminomethyl)-9-phenanthrenemethanols K. Venkatramana Bhat, Silvano L. De Bernardo, and W. Werner Zorbach pp 536 - 538; DOI: 10.1021/jm00303a620 |
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Notes. Ester of Undecanoic Acid with Potential Long-Lasting Insect-Repellent Activity Lorrin R. Garson, and Ronald P. Quintana pp 538 - 540; DOI: 10.1021/jm00303a621 |
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Notes. Synthesis and Antitumor Activity of 9-Substituted Nitrogen Mustard Derivatives of Naturally Occurring Purines Darrell E. O'Brien, Ronald K. Robins, James D. Westover, and C. C. Cheng pp 540 - 542; DOI: 10.1021/jm00303a622 |
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Notes. Antineoplastic Agents. XXV. 1,4-Diazabicyclo[2.2.1]heptanes Dyral C. Fessler, George R. Pettit, and Joseph A. Settepani pp 542 - 543; DOI: 10.1021/jm00303a623 |
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Notes. Fluorinated Pyrimidines. XXXII. Syntheses of 2',3'-Dehydro-5-trifluoromethyl-2'-deoxyuridine and 5-Trifluoromethyluridine Tasneem A. Khwaja, and Charles Heidelberger pp 543 - 545; DOI: 10.1021/jm00303a624 |
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Notes. Pyrazoles. III. Antileukemic Activity of 3-(3,3,-Dimethyl-1-triazeno)pyrazole-4-carboxamide C. Wayne Noell, and C. C. Cheng pp 545 - 546; DOI: 10.1021/jm00303a625 |
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Notes. Synthesis of Fatty Acids with Smooth Muscle Stimulant Activity. II. Myristoylbutyrolactones and Analogs E. Crundwell, and P. Farmer pp 547 - 548; DOI: 10.1021/jm00303a626 |
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Notes. 3-Deoxy Progestins Arvin P. Shroff pp 548 - 549; DOI: 10.1021/jm00303a627 |
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Notes. 2-Hydroxy-2-phenylethylhydrazine Monoamine Oxidase Inhibitors Charles F. Barfknecht, Gerald Pirch, William M. McIsaac, and Beng T. Ho pp 549 - 550; DOI: 10.1021/jm00303a628 |
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Notes. Thiomethyltetrazole Hypoglycemic Agents J. M. McManus pp 550 - 551; DOI: 10.1021/jm00303a629 |
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Notes. Potential Antihypertensive Agents. IV. Unsymmetrically 1,4-Disubstituted Piperazines. II. Raj Nandan Prasad, and Karin Tietje pp 551 - 552; DOI: 10.1021/jm00303a630 |
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New Compounds. Possible Anthelmintic Thiazol-5-ylbenzimidazoles. III J. M. Singh pp 553 - 553; DOI: 10.1021/jm00303a631 |
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New Compounds. Synthesis of Some New 6-Chloro-S-substituted 2-Mercapto-3-aryl- (or alkyl-) 4(3H)-quinazolones as Antimalarials P. N. Bhargava, and V. N. Choubey pp 553 - 554; DOI: 10.1021/jm00303a632 |
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New Compounds.Tetraiodophthaloyl Amino Acids Charles J. Jarboe, and Francis B. Alvey pp 555 - 555; DOI: 10.1021/jm00303a633 |
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New Compounds. 1-Substituted 4-Aryl- (or 4-Aralkyl-) phthalazines H. M. Holava, Jr., and R. A. Partyka pp 555 - 556; DOI: 10.1021/jm00303a634 |
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New Compounds. Stereoisomeric 2,2'-Bithiiranes Peter W. Feit pp 556 - 557; DOI: 10.1021/jm00303a635 |
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New Compounds. Derivatives of 4-Aminobenzenesulfonanilide Carlos Rodriguez-Salazar pp 557 - 557; DOI: 10.1021/jm00303a636 |
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New Compounds. Perparation of Some ω-N-(Substituted Benzyl)aminoalkylpyridines O. H. Hankovszky, and K. Hideg pp 557 - 558; DOI: 10.1021/jm00303a637 |
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New Compounds. Synthesis of Some New N-o-Tolyl-N'-2-(substituted) Benzothiazolylguanidines P. N. Bhargava, and Harihar Singh pp 558 - 559; DOI: 10.1021/jm00303a638 |
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Book Reviews Alfred Burger, Ian E. Bush, T. F. Sholz, and J. H. Boothe pp 559 - 562; DOI: 10.1021/jm00303a639 |
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Bridgehead nitrogen compounds as potential analgetics Arnold H. Beckett, R. G. Lingard, and A. E. E. Theobald pp 563 - 568; DOI: 10.1021/jm00304a001 |
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Conformation of some 1-azabicycloalkanols R. G. Lingard, Arnold H. Beckett, and A. E. E. Theobald pp 569 - 574; DOI: 10.1021/jm00304a002 |
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Tetrahydroisoquinolines. I. Preparation and analgetic activity of some 1-[2-(phenylthio)ethyl]tetrahydroisoquinolines and 1-(2-phenoxyethyl)tetrahydroisoquinolines Thomas A. Montzka, Nancy M. Cladel, and John D. Matiskella pp 575 - 580; DOI: 10.1021/jm00304a003 |
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Analgetic activity of cyclized basic anilides Herbert J. Havera, J. W. VanDyke, T. M. H. Liu, and L. F. Sancilio pp 580 - 583; DOI: 10.1021/jm00304a004 |
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Synthesis and analgetic activity of some 1-substituted 3-pyrrolidinylanilides and dihydrobenzoxazinones Grover C. Helsley, Carl D. Lunsford, William J. Welstead, Robert F. Boswell, William H. Funderburk, and David N. Johnson pp 583 - 586; DOI: 10.1021/jm00304a005 |
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Heterocyclic mesoionic structures, a novel class of monoamine oxidase inhibitors. II. Arylanhydro-1,2,3-thiadiazolium hydroxides Edward H. Wiseman and Donald P. Cameron pp 586 - 591; DOI: 10.1021/jm00304a006 |
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Repository drugs. VI. 4'-[N-(Aralkylidene-, -benzylidene-, and-naphthylidene)sulfanilyl]anilides, 4'-[N-[(dimethylamino)methylene]sulfanilyl]anilides, and related sulfanilylanilides with prolonged antimalarial and antileprotic action Donald F. Worth, Edward F. Elslager, and Annette A. Phillips pp 591 - 596; DOI: 10.1021/jm00304a007 |
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Repository drugs. VII. N-Allylidene-4,4'-sulfonyldianiline and N-(benzylidene- and -1-naphthylmethylene)-N'-methylene-4,4'-sulfonyldianiline polymers with prolonged antimalarial and antileprotic action Edward F. Elslager, David B. Capps, and Donald F. Worth pp 597 - 599; DOI: 10.1021/jm00304a008 |
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Repository drugs. VIII. Ester and amide congeners of amodiaquine, hydroxychloroquine, oxychloroquine, primaquine, quinacrine, and related substances as potential long-acting antimalarial agents Edward F. Elslager, Frank H. Tendick, and Leslie M. Werbel pp 600 - 607; DOI: 10.1021/jm00304a009 |
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Comparison of schistosomicidal activity of xanthenones and 4-methyl-3-chloroanilines and their hydroxymethyl analogs in Swiss mice and Syrian hamsters infected with Schistosma mansoni Dicran A. Berberian, Emery W. Dennis, Hugh W. Freele, David Rosi, Thomas Richard Lewis, Roman R. Lorenz, and Sydney Archer pp 607 - 610; DOI: 10.1021/jm00304a010 |
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Isoxazole chemistry. I. 3- or 5-(5-Nitro-2-furyl)-5- or -3-methylisoxazoles Ronald G. Micetich pp 611 - 616; DOI: 10.1021/jm00304a011 |
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Cyclic disulfides. II. 1,2-Dithiepan-5-amine H. F. Herbrandson and Rebecca H. Wood pp 617 - 620; DOI: 10.1021/jm00304a012 |
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Cyclic disulfides. III. (-)-(S)-1,2-dithiepan-4-amine and related compounds H. F. Herbrandson and Rebecca H. Wood pp 620 - 624; DOI: 10.1021/jm00304a013 |
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Biologically oriented organic sulfur chemistry. II. Formation of hemimercaptals or hemimercaptoles (.alpha.-hydroxy sulfides) as a means of latentiating thiols Lamar Field, B. J. Sweetman, and Michael Bellas pp 624 - 628; DOI: 10.1021/jm00304a014 |
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Thia steroids. I. 2-Thia-A-nor-5.alpha.-androstan-17.beta.-ol, an active androgen Manfred E. Wolff and Galal Zanati pp 629 - 631; DOI: 10.1021/jm00304a015 |
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Synthesis and progestational activity of some 1,2.alpha.-cyclomethylene-16-methylene progesterone derivatives Elliot L. Shapiro, T. L. Popper, Lois Weber, R. Neri, and H. L. Herzog pp 631 - 636; DOI: 10.1021/jm00304a016 |
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Tricyclic analogs of melatonin T. Kobayashi, T. F. Spande, H. Aoyagi, and Bernhard Witkop pp 636 - 638; DOI: 10.1021/jm00304a017 |
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.beta.-Adrenergic blocking agents. V. 1-Amino-3-(substituted phenoxy)-2-propanols Albert F. Crowther, D. J. Gilman, B. J. McLoughlin, Leslie Harold Smith, R. W. Turner, and T. M. Wood pp 638 - 642; DOI: 10.1021/jm00304a018 |
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.beta.-Adrenergic blocking agents. VI. Pronethalol and propranolol analogs with alkyl substituents in the alkanol side chain Ralph Howe pp 642 - 646; DOI: 10.1021/jm00304a019 |
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Steric parameters in drug design. Monoamine oxidase inhibitors and antihistamines Eberhard Kutter and Corwin Hansch pp 647 - 652; DOI: 10.1021/jm00304a020 |
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Synthesis and biological activity of certain 8-mercaptopurine and 6-mercaptopyrimidine S-nucleosides Dennis A. Shuman, Alexander Bloch, Roland K. Robins, and Morris J. Robins pp 653 - 657; DOI: 10.1021/jm00304a021 |
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Purine nucleosides. XXV. Synthesis of certain derivatives of 5'-amino-5'-deoxy- and 5'-amino-2',5'-dideoxy-.beta.-D-ribofuranosylpurines as purine nucleotide analogs Mason G. Stout, Morris J. Robins, Richard K. Olsen, and Roland K. Robins pp 658 - 662; DOI: 10.1021/jm00304a022 |
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Dihydrofolate reductase from Trypanosoma equiperdum. II. Inhibition by 2,4-diaminopyrimidines and related heterocycles John J. McCormack and Julian J. Jaffe pp 662 - 668; DOI: 10.1021/jm00304a023 |
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Irreversible enzyme inhibitors. CLIV. Some factors in cell wall transport of active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-substituted 2,4-diaminopyrimidines Bernard Randall Baker and Rich B. Meyer pp 668 - 671; DOI: 10.1021/jm00304a024 |
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Irreversible enzyme inhibitors. CLV. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 1-[4-.omega.-aminoalkoxy)-3-chlorophenyl]-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazines bearing a terminal sulfonyl fluoride Bernard Randall Baker and Eunice E. Janson pp 672 - 676; DOI: 10.1021/jm00304a025 |
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Irreversible enzyme inhibitors. CLVI. Proteolytic enzymes. XII. Inhibitors of guinea pig complement derived by quaternization of 3-acylamidopyridines with .alpha.-bromomethylbenzenesulfonyl fluorides Bernard Randall Baker and Jeffrey A. Hurlbut pp 677 - 680; DOI: 10.1021/jm00304a026 |
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Irreversible enzyme inhibitors. CLVII. Effect of bridge modification on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-[m-(fluorosulfonyl)benzamidomethyl]phenoxymethyl]pyrimidine. I Bernard Randall Baker and Nicolaas M. J. Vermeulen pp 680 - 684; DOI: 10.1021/jm00304a027 |
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Irreversible enzyme inhibitors. CLVIII. Effect of bridge modification on the selective irreversible inhibition of a dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-[m-(fluorosulfonyl)benzamidomethyl]phenoxymethyl]pyrimidine. II Bernard Randall Baker and Nicolaas M. J. Vermeulen pp 684 - 688; DOI: 10.1021/jm00304a028 |
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Thyroxine analogs. XVII. 3,5-Bis(ethylthio)- and 3,5-bis(phenylthio)-DL-thyronines and their 3'-isopropyl analogs Eugene C. Jorgensen, Richard O. Muhlhauser, and Robert A. Wiley pp 689 - 691; DOI: 10.1021/jm00304a029 |
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Superdelocalizability and charge density. A correlation with partition coefficients Kenneth S. Rogers and Arthur Cammarata pp 692 - 693; DOI: 10.1021/jm00304a030 |
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Iodinated derivatives of histamine and N-acetylhistamine Mineko Tominaga and Antonio C. M. Paiva pp 693 - 694; DOI: 10.1021/jm00304a031 |
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Synthesis of heterocyclic compounds. CCLXXXXV. Syntheses of benzomorphan and related compounds. II. The debenzylation of quaternary ammonium salts with thiophenol Tetsuji Kametani, Kazuo Kigasawa, Mineharu Hiiragi, Nagatoshi Wagatsuma, Kikuo Wakisaka, and O. Kusama pp 694 - 696; DOI: 10.1021/jm00304a032 |
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Sulfamoylbenzoic acid ester derivatives as potential local anesthetics. I N. Sharghi, I. Lalezari, G. Niloofari, and H. Golgolab pp 696 - 697; DOI: 10.1021/jm00304a033 |
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Inhibition of cholesterolgenesis in vitro by chlorophenoxyacetic acids. Effect of .alpha.-methyl groups Donald T. Witiak, Robert E. Hackney, and Michael W. Whitehouse pp 697 - 699; DOI: 10.1021/jm00304a034 |
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2-Benzyl-5-aminolevulinic acid, an analog of glycyl-DL-phenylalanine Sherrel C. Smith and Floyd W. Dunn pp 699 - 700; DOI: 10.1021/jm00304a035 |
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2-Benzyl-5-(dimethylamino)-.gamma.-valerolactone, an inhibitor of plasma cholinesterase Sherrel C. Smith and Floyd W. Dunn pp 701 - 701; DOI: 10.1021/jm00304a036 |
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N4,N4'-Decamethylenebis(4-aminopyridine) and N9,N9'-decamethylenebis(9-aminoacridine) John P. Paolini, Louis J. Lendvay, and Frank P. Palopoli pp 701 - 702; DOI: 10.1021/jm00304a037 |
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N1-Sulfato-N2-isonicotinoylhydrazine. A potential metabolite of isoniazid John Henry Peters pp 702 - 703; DOI: 10.1021/jm00304a038 |
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Preparation and antibacterial activity of .alpha.-(5-tetrazolyl)benzylpenicillin John M. Essery pp 703 - 705; DOI: 10.1021/jm00304a039 |
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Tetracyclic phenothiazines. II. Antibacterial evaluation of 3-oxo-3H-pyrido[3,2,1-kl]phenothiazine-2-carboxylate Te-Sheng Huang, Timothy J. Yale, and Arnold R. Martin pp 705 - 707; DOI: 10.1021/jm00304a040 |
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Bacteriostatic effectiveness of 1-acyl-3-(3,4-dichlorophenyl)ureas Moneeb H. Zakaria and David Taber pp 707 - 708; DOI: 10.1021/jm00304a041 |
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Nitroheterocycles. I. Nitrofuryl-substituted 3-amino-1,2,4-oxadiazoles and 5-amino-1,2,4-oxadiazoles Hermann Breuer pp 708 - 709; DOI: 10.1021/jm00304a042 |
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Antimalarial compounds related to diaminodiphenyl sulfone Henry Bader, John F. Hoops, John H. Biel, Harlen H. Koelling, Robert G. Stein, and Tara Singh pp 709 - 711; DOI: 10.1021/jm00304a043 |
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2-(.omega.-Aminoalkyl)-4-tert-butyl-6-phenylphenols as antimalarial agents Warren G. Duncan and David W. Henry pp 711 - 712; DOI: 10.1021/jm00304a044 |
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Synthesis and antiviral properties of 1-adamantylguanidine. A modified method for preparing tert-alkylguanidines H. W. Geluk, J. Schut, and J. L. M. A. Schlatmann pp 712 - 715; DOI: 10.1021/jm00304a045 |
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1-Adamantanecarboxylic acid ester of scopolamine Robert B. Moffett pp 715 - 715; DOI: 10.1021/jm00304a046 |
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Structure-activity studies of 3,4,5-trimethoxybenzamides. I. Variation of the amine function Wilfred A. Skinner, J. Kennedy, Joseph I. DeGraw, and Howard Johnson pp 715 - 717; DOI: 10.1021/jm00304a047 |
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Purine N-oxides. XXIX. Synthesis of 6-(hydroxyamino)purine 3-oxide and related derivatives Alfredo Giner-Sorolla pp 717 - 719; DOI: 10.1021/jm00304a048 |
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Nitrones. I. .alpha.-(5-Nitro-2-furyl)-N-arylnitrones H. K. Kim and R. E. Bambury pp 719 - 720; DOI: 10.1021/jm00304a049 |
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Benzylideneindenes with oxygen attached to the indene ring Carl T. Bahner, David H. Brotherton, and Harold Kinder pp 721 - 722; DOI: 10.1021/jm00304a050 |
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6-(Dimethylamino)chrysene and other analogs of 4-(4-dimethylamino)stilbene Carl T. Bahnr, David H. Brotherton, Harold Kinder, William Rich, Stuart L. Watson, and John Zirkle pp 722 - 722; DOI: 10.1021/jm00304a051 |
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9-(4-Aminobenzylidene)fluorenes Carl T. Bahner and David H. Brotherton pp 722 - 723; DOI: 10.1021/jm00304a052 |
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Potential antiradiation agents. II. Guanidinoalkanethiosulfuric acids Daniel L. Klayman, Marie M. Grenan, and David P. Jacobus pp 723 - 725; DOI: 10.1021/jm00304a053 |
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Terpene compounds as drugs. VI. Acyclic mono- and sesquiterpene thiocyanates and isothiocyanates Gianfranco Pala, Antonio Mantegani, and Germano Coppi pp 725 - 726; DOI: 10.1021/jm00304a054 |
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Synthesis of certain 3,5-dimethyl-N1-(arylsulfonyl)pyrazoles and 3-methyl-N1-(arylsulfonyl)-5-pyrazolones Carlos Sunkel and Mariana Sanchez pp 726 - 727; DOI: 10.1021/jm00304a055 |
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(Carboxymethyl)cyclohexyldimethylammonium chloride hydrazide T. A. McGuire and C. L. Mehltretter pp 727 - 727; DOI: 10.1021/jm00304a056 |
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3,3-Disubstituted ethyl carbazates Walter Thomas Smith and Wen-Yean Chen pp 727 - 728; DOI: 10.1021/jm00304a057 |
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Proving New Drugs-A Guide to Clinical Trials Alfred Burger pp 729 - 729; DOI: 10.1021/jm00304a900 |
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Anabolic Steroids Raymond E. Counsell pp 729 - 729; DOI: 10.1021/jm00304a901 |
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Progress in Drug Research. Volume 12 Alfred Burger pp 729 - 730; DOI: 10.1021/jm00304a902 |
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Two Views of Drug Abuse. 1. Amphetamine Abuse Alfred Burger pp 730 - 730; DOI: 10.1021/jm00304a903 |
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Two Views of Drug Abuse. II. Drug Abuse. A Course for Educators Alfred Burger pp 730 - 730; DOI: 10.1021/jm00304a904 |
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Synthesis and some pharmacological activities of [2-L-valine]-oxytocin and [2-L-leucine]-oxytocin Victor J. Hruby and Vincent Du Vigneaud pp 731 - 733; DOI: 10.1021/jm00305a001 |
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Angiotensin II analogs. I. Synthesis and biological evaluation of [Gly1,Gly2,Ile5]-angiotensin II, [Ac-Gly1,Gly2,Ile5]-angiotensin II, and [Gly1,Gly2,Ile5,His(Bzl)6]-angiotensin II Eugene C. Jorgensen, Graham C. Windridge, Walter Patton, and Thomas Choy Lee pp 733 - 737; DOI: 10.1021/jm00305a002 |
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Synthesis and microbiological properties of dipeptides containing cyclopentaneglycine and .beta.-2-thienylalanine Jim Tom Hill and Floyd W. Dunn pp 737 - 740; DOI: 10.1021/jm00305a003 |
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Kinetics and mechanisms of action of drugs on microorganisms. VIII. Quantification and prediction of the biological activities of meta- and para-substituted N1-phenylsulfanilamides by microbial kinetics Edward R. Garrett, Jobst B. Mielck, Joachim K. Seydel, and Hans J. Kessler pp 740 - 745; DOI: 10.1021/jm00305a004 |
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Homolytic constants in the correlation of chloramphenicol structure with activity Corwin Hansch, Eberhard Kutter, and A. Leo pp 746 - 749; DOI: 10.1021/jm00305a005 |
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Structure-activity relationships among substrates for a rabbit kidney reductase. Quantum chemical calculation of substituent parameters Robert B. Hermann, Hilman W. Culp, Robert E. McMahon, and Max M. Marsh pp 749 - 754; DOI: 10.1021/jm00305a006 |
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Species difference in the competitive binding of 2-(4'-hydroxybenzeneazo)benzoic acid (HBABA) and .alpha.-(4-chlorophenoxy)-.alpha.-methylpropionic acid (CPMPA) to serum albumin. A possible model system for studying allosteric transitions Donald T. Witiak, Theodore D. Sokoloski, Michael W. Whitehouse, and Freya Hermann pp 754 - 761; DOI: 10.1021/jm00305a007 |
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Molecular orbital calculations on anticonvulsant drugs P. R. Andrews pp 761 - 764; DOI: 10.1021/jm00305a008 |
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Molecular orbital calculations on a new series of substituted-phenyl choline ethers James Crow, Otmar Wassermann, and William C. Holland pp 764 - 766; DOI: 10.1021/jm00305a009 |
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Comparison of parameters currently used in the study of structure-activity relationships A. Leo, Corwin Hansch, and C. Church pp 766 - 771; DOI: 10.1021/jm00305a010 |
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Potential antitumor agents. II. Effects of modifications in the side chain of 1-formylisoquinoline thiosemicarbazone Krishna C. Agrawal and Alan C. Sartorelli pp 771 - 774; DOI: 10.1021/jm00305a011 |
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Synthesis and relationship between structure and activity of 2-nitroimidazole derivatives Gian C. Lancini, Ettore Lazzari, V. Arioli, and P. Bellani pp 775 - 780; DOI: 10.1021/jm00305a012 |
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Lincomycin. VIII. 4'-Alkyl-1'-demethyl-4'-depropylclindamycins, potent antibacterial and antimalarial agents Barney J. Magerlein and Fred Kagan pp 780 - 784; DOI: 10.1021/jm00305a013 |
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Preparation and antimycotic properties of derivatives of 1-phenethylimidazole Erik F. Godefroi, Jan Heeres, Jan Van Cutsem, and Paul A. J. Janssen pp 784 - 791; DOI: 10.1021/jm00305a014 |
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Imidoylureas. A new class of anthelmintics Guy D. Diana, Allen Yarinsky, Ethel S. Zalay, Dicran A. Berberian, and Samuel Schalit pp 791 - 793; DOI: 10.1021/jm00305a015 |
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Imidazolylphosphonamidochloridothionates Paul B. Budde and Henry Tolkmith pp 794 - 796; DOI: 10.1021/jm00305a016 |
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Diaminoquinoline antimalarials Ned D. Heindel, Ibrahim S. Bechara, Cyrus J. Ohnmacht, James Molnar, Thomas F. Lemke, and Peter D. Kennewell pp 797 - 801; DOI: 10.1021/jm00305a017 |
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Antimalarials. 4-Proximal hydrazino derivatives of 7-chloroquinoline Tara Singh, Robert G. Stein, and John H. Biel pp 801 - 803; DOI: 10.1021/jm00305a018 |
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Imidazolecarbohydrazides. III. Chemistry and biological evaluation J. R. Nulu and Jay Nematollahi pp 804 - 806; DOI: 10.1021/jm00305a019 |
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Anthelmintic quaternary salts. IV. Aminopentadienylideneammonium salts David L. Garmaise, Gerard Y. Paris, Jacqueline Komlossy, and R. C. McCrae pp 806 - 810; DOI: 10.1021/jm00305a020 |
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Steroids. LXXXIII. Effects of some steroidal alkylating agents on experimental animal mammary tumor and leukemia systems Monroe E. Wall, G. Shuford Abernethy, F. I. Carroll, and Dorothy Jane Taylor pp 810 - 818; DOI: 10.1021/jm00305a021 |
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Fluorescent alkylating agents. 1-(.beta.-chloroethyl)bisbenzimidazoles Kwan Chung Tsou, Dorothy J. Rabiger, and Barbara Sobel pp 818 - 822; DOI: 10.1021/jm00305a022 |
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Derivatives of fluorene. XXX. Rearrangement and antitumor activities of some 9-oxofluorene oximes. 6(5H)-phenanthridinones. 1 Hsi-Lung Pan and T. Lloyd Fletcher pp 822 - 825; DOI: 10.1021/jm00305a023 |
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Potential carcinolytic agents. VII. Substituted bis(2-methanesulfonoxyethyl)anilines Zion B. Papanastassiou, Robert J. Bruni, Peggy B. Estes, and Isidore Wodinsky pp 825 - 828; DOI: 10.1021/jm00305a024 |
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Charge-spatial models. cis- and trans-3- and -4-Substituted cyclohexyl phosphates as analogs of 2'-deoxyuridine 5'-phosphate Mathias P. Mertes and Eugene A. Coats pp 828 - 832; DOI: 10.1021/jm00305a025 |
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Physicochemical model for the mechanism of action of antihistaminics and cortisol Claudio Botre, Marcello Marchetti, Camillo Del Vecchio-Blanco, G. Lionetti, and Adriana Memoli pp 832 - 836; DOI: 10.1021/jm00305a026 |
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Bicyclic homologs of piperazine. IX. Synthesis and pharmacological properties of phenothiazine and of 10,11-dihydrodibenzocycloheptene derivatives of 3,8-diazabicyclo[3.2.1]octanes Giorgio Cignarella, Emilio Occelli, Giulio Maffii, and Emilio Testa pp 836 - 839; DOI: 10.1021/jm00305a027 |
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Stereochemical studies on medicinal agents. VII. Absolute stereochemistry of methadol isomers and the role of the 6-methyl group in analgetic activity Philip S. Portoghese and David Allen Williams pp 839 - 844; DOI: 10.1021/jm00305a028 |
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1,2,3,4,5,6-Hexahydro-6-phenyl-2,6-methano-3-benzazocines. I. 3-Carboxamido-8-hydroxy derivative as an orally effective analgetic Fred B. Block and Frank Henderson Clarke pp 845 - 847; DOI: 10.1021/jm00305a029 |
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3-Acetoxyquinuclidine methiodide. Resolution, absolute configuration, and stereospecificity of interaction with the acetylcholine binding sites John Barry Robinson, Bernard Belleau, and Barry Cox pp 848 - 851; DOI: 10.1021/jm00305a030 |
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2-(N,N-dialkylamino)ethyl esters of .alpha.-(3-pyridyl)mandelic acids. Synthesis and pharmacological evaluation Armando Novelli, Jorge R. Barrio, and H. Huidobro pp 851 - 854; DOI: 10.1021/jm00305a031 |
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Malonamic esters. New class of sedative-tranquilizers Bernard Loev, Edward Macko, and Irving M. Fried pp 854 - 859; DOI: 10.1021/jm00305a032 |
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Synthesis and central nervous system depressant activity of new piperazine derivatives and related compounds. II D. J. Vadodaria, Chimanlal V. Deliwala, S. S. Mandrekar, and U. K. Sheth pp 860 - 865; DOI: 10.1021/jm00305a033 |
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Synthesis and central nervous system depressant activity of new piperazine and related derivatives. III R. B. Petigara, Chimanlal Deliwala, S. S. Mandrekar, N. K. Dadkar, and U. K. Sheth pp 865 - 870; DOI: 10.1021/jm00305a034 |
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Synthesis and pharmacological activity of alkylaminoalkyl esters and amides of 2-hydroxy- (or alkoxy-) 3-methoxybenzoic acid Georges Tsatsas, E. Costakis, John F. Zaroslinski, Ronald K. Browne, and Leroy H. Possley pp 870 - 873; DOI: 10.1021/jm00305a035 |
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Synthesis and antialdosterone activity of substituted 2,3,3-triphenylpropylamines Benjamin Blank, William A. Zuccarello, Suzanne R. Cohen, Gertrude J. Frishmuth, and Daniel Scaricaciottoli pp 873 - 876; DOI: 10.1021/jm00305a036 |
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Psychosedative agents. N-(4-phenyl-1-piperazinylalkyl)-substituted cyclic imides Yao-Hua Wu, Kenneth R. Smith, James W. Rayburn, and John W. Kissel pp 876 - 881; DOI: 10.1021/jm00305a037 |
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Mammalian antifertility agents. VI. A novel sequence for the preparation of 1,2-disubstituted 3,4-dihydronaphthalenes Daniel Lednicer, D. Edward Emmert, Stanley C. Lyster, and Gordon W. Duncan pp 881 - 885; DOI: 10.1021/jm00305a038 |
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3-Deoxy-16-haloestra-1,3,5(10)-trienes William F. Johns pp 885 - 888; DOI: 10.1021/jm00305a039 |
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Biologically oriented organic sulfur chemistry. III. Formation of mercaptals, mercaptoles, an orthothioformate, and thiazolidines for the latentiation of thiols B. J. Sweetman, Michael Bellas, and Lamar Field pp 888 - 891; DOI: 10.1021/jm00305a040 |
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Quaternary thiazolylpyridinium salts. Oral hypoglycemic agents Gretchen E. Wiegand, Victor J. Bauer, Sidney R. Safir, D. A. Blickens, and S. J. Riggi pp 891 - 893; DOI: 10.1021/jm00305a041 |
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Irreversible enzyme inhibitors. CLIX. Effect of substitution on transport and isozyme specificity of p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)-o-chlorophenoxyacetamido-benzenesulfonyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase Bernard Randall Baker and Wallace T. Ashton pp 894 - 897; DOI: 10.1021/jm00305a042 |
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Irreversible enzyme inhibitors. CLX. Some factors in cell wall transport of active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(phenylalkylphenyl)-s-triazines Bernard Randall Baker, Eunice E. Janson, and Nicolaas M. J. Vermeulen pp 898 - 902; DOI: 10.1021/jm00305a043 |
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Irreversible enzyme inhibitors. CLXI. Proteolytic enzymes. 13. Inhibitors of guinea pig complement derived by quaternization of 3-acylamidopyridines with .alpha.-bromomethylbenzenesulfonyl fluorides Bernard Randall Baker and Jeffrey A. Hurlbut pp 902 - 905; DOI: 10.1021/jm00305a044 |
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Monoquaternary muscle paralyzing agents. III. Synthesis of N-(.omega.-phthalimidoalkyl)trialkylammonium iodides Hugh B. Donahoe, Robert J. Seiwald, Sister Mary Marguerite Neumann, Donald E. Heitmeier, and Kazuo K. Kimura pp 906 - 907; DOI: 10.1021/jm00305a045 |
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Some organoboron compounds containing a bis(2-chloroethyl)amino group joined to boron Y. Fulmer Shealy and Robert F. Struck pp 907 - 911; DOI: 10.1021/jm00305a046 |
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Compounds related to insect juvenile hormone. IV Nobel Wakabayashi, Philip E. Sonnet, and M. W. Law pp 911 - 913; DOI: 10.1021/jm00305a047 |
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Synthesis of some substituted 5H-dibenz[b,f]azepines as potential antimalarials Rajendra S. Varma, L. K. Whisenant, and David W. Boykin pp 913 - 914; DOI: 10.1021/jm00305a048 |
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1,3-Dihydro-1-methyl-5,6- (and 5,7-) diaryl-2H-1,4-diazepin-2-ones Corris Mabelle Hofmann and Sidney R. Safir pp 914 - 917; DOI: 10.1021/jm00305a049 |
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Steric structure-activity relationship studies on a new butyrophenone derivative J. Pengman Li and John H. Biel pp 917 - 919; DOI: 10.1021/jm00305a050 |
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Synthesis of compounds with potential central nervous system stimulant activity. I. 2-Amino-2-oxazolin-4-one-5-spirocycloalkanes and 2-amino-2-oxazolin-4-one-5-spiro(4'-piperidines) Michael R. Harnden and Ray R. Rasmussen pp 919 - 921; DOI: 10.1021/jm00305a051 |
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N-aminonormorphine Ali Modiri, Joseph G. Cannon, and S. Y. Yeh pp 921 - 922; DOI: 10.1021/jm00305a052 |
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Receptor binding of the analgetic aryl moiety. I. .alpha.-Prodine analogs Khalid Sabih and Robert A. Wiley pp 922 - 923; DOI: 10.1021/jm00305a053 |
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Biochemorphology of cyclobutanecarboximides Karimullah A. Zirvi and Charles H. Jarboe pp 923 - 925; DOI: 10.1021/jm00305a054 |
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Isolation and identification of cephalexin from human urine Ta-Sen Chou pp 925 - 926; DOI: 10.1021/jm00305a055 |
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Diamides of cyclobutane-1,1-dicarboxylic acid Karimullah A. Zirvi and Charles H. Jarboe pp 926 - 927; DOI: 10.1021/jm00305a056 |
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Substituted chromones as coronary vasodilators Dilbagh S. Bariana pp 927 - 928; DOI: 10.1021/jm00305a057 |
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N-[3-(1-alkylpiperidyl)]acetamides and N,N-dimethyl-N'-[3-(1-alkyl-piperidyl)]ureas as cholinesterase inhibitors. I Ian W. Mathison, James G. Beasley, Kathleen C. Fowler, and Elizabeth R. Peters pp 928 - 931; DOI: 10.1021/jm00305a058 |
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The cholinergic receptor. IV. Synthesis and muscarinic activity of 3,7-dimethyl-2,4-dioxa-7-azaspiro[3,4]octane methiodide Horace F. Ridley, Shym S. Chatterjee, John F. Moran, and David J. Triggle pp 931 - 933; DOI: 10.1021/jm00305a059 |
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Derivatives of 2-azabicyclo[2.2.2]octane. III. Substituted phenylsulfonylureido derivatives Frank J. Villani, Elizabeth A. Wefer, Thomas A. Mann, and Claire A. Ellis pp 933 - 934; DOI: 10.1021/jm00305a060 |
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Angiotensin II analogs. II. Cyclo-(-Val-Tyr-Ile-His-Pro-Phe-) Eugene C. Jorgensen and Walter Patton pp 935 - 936; DOI: 10.1021/jm00305a061 |
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Hypotensive, antiadrenergic, and antihistaminic 3-substituted 2-methyl-(or 2-phenyl-) 4(3H)-quinazolones Shin Hayao, H. J. Havera, W. G. Strycker, and Enrique Hong pp 936 - 938; DOI: 10.1021/jm00305a062 |
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meta-Substituted benzenesulfonylureas as hypoglycemic agents Madhusudan H. Shah, T. V. Darnule, Kodaganallur G. Ananthanarayanan, and Chimanlal V. Deliwala pp 938 - 939; DOI: 10.1021/jm00305a063 |
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.beta.-Aminopropionohydroxamic acids and .beta.-aminopropionic esters with hypotensive properties Ronald T. Coutts, Kamal K. Midha, and K. Prasad pp 940 - 941; DOI: 10.1021/jm00305a064 |
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Hypoglycemic esters of 2-chloroethanol James E. Siggins, Homer R. Harding, and Gordon O. Potts pp 941 - 943; DOI: 10.1021/jm00305a065 |
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Quaternary oxazolylpyridinium salts. Oral hypoglycemic agents Gretchen E. Wiegand, Victor J. Bauer, Sidney R. Safir, D. A. Blickens, and S. J. Riggi pp 943 - 944; DOI: 10.1021/jm00305a066 |
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Hypoglycemic quaternary azolylpyridinium salts. Inactive analogs Victor J. Bauer, Gretchen E. Wiegand, William J. Fanshawe, and Sidney R. Safir pp 944 - 945; DOI: 10.1021/jm00305a067 |
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4-Azolylpyridine 1-oxides. Analogs of the hypoglycemic 4-azolylpyridinium salts Victor J. Bauer, William J. Fanshawe, Gretchen E. Wiegand, and Sidney R. Safir pp 945 - 946; DOI: 10.1021/jm00305a068 |
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5,5-Diarylpenta-2,4-dienoic acid amides as potential antimalarial agents. II Judy Hayford Lange, William T. Colwell, and David W. Henry pp 946 - 947; DOI: 10.1021/jm00305a069 |
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Synthesis and antiinflammatory activity of 5-substituted 2,3-bis(p-methoxyphenyl)indoles Gilbert A. Youngdale, E. Myles Glenn, Daniel Lednicer, and Jacob Szmuszkovicz pp 948 - 949; DOI: 10.1021/jm00305a070 |
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Antimalarials. Chloroquine analogs with the 1,2,3,6-tetrahydropyridyl function in the side chain Tara Singh, Robert G. Stein, and John H. Biel pp 949 - 950; DOI: 10.1021/jm00305a071 |
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N-Acyl- and N-sulfonylcysteine derivatives Tellis A. Martin pp 950 - 953; DOI: 10.1021/jm00305a072 |
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Amides of N-acylcysteines as potential amino acid antagonists in bacteria Walter A. Zygmunt and Tellis A. Martin pp 953 - 955; DOI: 10.1021/jm00305a073 |
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Synthetic amebicides. X. Antiamebic, antimalarial, and anthelmintic effects of distal hydrazine analogs of azacrine, quinacrine, and 7-{ [3-(octylamino)propyl]amino}benz[c]acridine Edward F. Elslager and Donald F. Worth pp 955 - 957; DOI: 10.1021/jm00305a074 |
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Trifluoromethylbenzanilides as anticoccidial agents Dean E. Welch and Robert R. Baron pp 957 - 959; DOI: 10.1021/jm00305a075 |
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Synthesis of 3,5-dihydroxy-4-methoxy-.alpha.-methylphenethanolamine and analogs Fred G. H. Lee, Donald E. Dickson, Joseph D. Benigni, R. L. Minnis, Walter F. Gannon, and Albert A. Manian pp 959 - 960; DOI: 10.1021/jm00305a076 |
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Oxidation of fluorenamines and preparation of 2,2'-and 4,4'-azofluorene Yul Yost pp 961 - 961; DOI: 10.1021/jm00305a077 |
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Stable oxaziridines Jyotirmoy Chakravarty and Price Truitt pp 961 - 962; DOI: 10.1021/jm00305a078 |
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Possible anticonvulsant thiazolo[3,2-a]benzimidazole Mannich bases. XI Jag Megh Singh pp 962 - 962; DOI: 10.1021/jm00305a079 |
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Progress in Biochemical Pharmacology. Volume 4. Recent Advances in Atherosclerosis Frederick L. Bach pp 963 - 963; DOI: 10.1021/jm00305a900 |
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Biogenesis and Action of Steroid Hormones Leonard R. Axelrod pp 963 - 963; DOI: 10.1021/jm00305a901 |
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Annual Review of Pharmacology. Volume 9 Alfred Burger pp 963 - 963; DOI: 10.1021/jm00305a902 |
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Psychopharmacology. A Review of Progress, 1957-1967 Alfred Burger pp 963 - 964; DOI: 10.1021/jm00305a903 |
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Principles of Radiological Health Alfred Burger pp 964 - 964; DOI: 10.1021/jm00305a904 |
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Antifilarial agents. I. Effects of 4-[(7-chloro-4-quinolyl)amino]-.alpha.-(mono- and dialkylamino)-o-cresols and related compounds against Litomosoides carinii in gerbils Edward F. Elslager, S. C. Perricone, and Frank H. Tendick pp 965 - 969; DOI: 10.1021/jm00306a001 |
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Antimalarial substances. XVIII. Synthetic schistosomicides. 13. Antimalarial and antischistosomal effects of proximal hydrazine and hydroxylamine analogs of chloroquine and quinacrine Edward F. Elslager, Frank H. Tendick, Leslie M. Werbel, and Donald F. Worth pp 970 - 974; DOI: 10.1021/jm00306a002 |
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Lincomycin. IX. 7-Thiol and thioamido analogs of lincomycin Barney J. Magerlein and Fred Kagan pp 974 - 977; DOI: 10.1021/jm00306a003 |
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Relation between structure, stereochemistry, and diuretic activity in the 2-amino-.alpha.-phenylcyclohexanemethanol series, a new class of diuretic agents. II Louis L. Skaletzky, B. E. Graham, and Jacob Szmuszkovicz pp 977 - 988; DOI: 10.1021/jm00306a004 |
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3-Halo-2-phenylglycidamide hypnotics J. B. Carr, G. R. Haynes, J. K. Kodama, and J. R. Albert pp 989 - 994; DOI: 10.1021/jm00306a005 |
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Analgetics. II. Relation between structure and activity of some .beta.-amino ketones Manmohan S. Atwal, Ludwig Bauer, S. N. Dixit, J. E. Gearien, M. Magahy, R. Morris, and C. Pokorny pp 994 - 997; DOI: 10.1021/jm00306a006 |
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Hypotensive agents. (+)- and (-)-2-2-Methoxy-2-(3-methoxyphenyl)ethylamine and related compounds Ralph Howe, Edwin H. P. Young, and A. D. Ainley pp 998 - 1001; DOI: 10.1021/jm00306a007 |
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Hypocholesterolemic 5-substituted tetrazoles Ronald L. Buchanan, Vilmars Sprancmanis, and Richard A. Partyka pp 1001 - 1006; DOI: 10.1021/jm00306a008 |
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Substituted phenylalkanoic acids and N-substituted malonanilic, succinanilic, and anilinoalkanoic acids as potential antiinflammatory agents Delme Evans, A. S. L. Mackintosh, and S. S. Szinai pp 1006 - 1010; DOI: 10.1021/jm00306a009 |
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Heterocyclic substituted ureas. I. Immunosuppression and virus inhibition by benzimidazolylureas Charles J. Paget, Kiem Kisner, Robert Louis Stone, and Donald C. DeLong pp 1010 - 1015; DOI: 10.1021/jm00306a010 |
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Heterocyclic substituted ureas. II. Immunosuppressive and antiviral activity of benzothiazolyl- and benzoxazolylureas Charles J. Paget, Kiem Kisner, Robert Louis Stone, and Donald C. DeLong pp 1016 - 1018; DOI: 10.1021/jm00306a011 |
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Potential coenzyme inhibitors. III. Some reactions of substituted nicotinamide and dihydronicotinamide derivatives Andrew C. Lovesey pp 1018 - 1023; DOI: 10.1021/jm00306a012 |
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Synthesis of 1-arylimidazoles, a new class of steroid hydroxylation inhibitors Alexander Lawrence Johnson, James C. Kauer, Dinesh Chandra Sharma, and R. I. Dorfman pp 1024 - 1028; DOI: 10.1021/jm00306a013 |
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Syntheses and substrate specificity for mammalian dihydroxyphenylalanine decarboxylase of 3-, 4-, 5-, and 6-methyl-2-hydroxyphenylalanines and the substrate specificity of 3-, 5-, and 6-methyl-2,4-dihydroxyphenylalanines for the enzyme Roger H. Bower and John P. Lambooy pp 1028 - 1030; DOI: 10.1021/jm00306a014 |
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Heterocyclic systems with a bridgehead nitrogen. II. 6-Chloroimidazo[2,1-b]thiazole and some of its 5-substituted derivatives John P. Paolini and Louis J. Lendvay pp 1031 - 1034; DOI: 10.1021/jm00306a015 |
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Synthesis and some pharmacological activities of 4-L-norvaline-oxytocin and 4-L-norleucine-oxytocin and their deamino analogs George Flouret and Vincent Du Vigneaud pp 1035 - 1038; DOI: 10.1021/jm00306a016 |
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Irreversible enzyme inhibitors. CLXII. Hydrophobic bonding to cytosine nucleoside deaminase with 1-substituted 5-arylcytosines Bernard Randall Baker and James L. Kelley pp 1039 - 1045; DOI: 10.1021/jm00306a017 |
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Irreversible enzyme inhibitors. CLXIII. Active-site-directed irreversible inhibitors of cytosine nucleoside deaminase derived from 1-phenoxypropyl-5-arylcytosines Bernard Randall Baker and James L. Kelley pp 1046 - 1049; DOI: 10.1021/jm00306a018 |
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Irreversible enzyme inhibitors. CLXIV. Proteolytic enzymes. 14. Inhibition of guinea pig complement by meta-substituted benzamidines Bernard Randall Baker and Michael Cory pp 1049 - 1052; DOI: 10.1021/jm00306a019 |
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Irreversible enzyme inhibitors. CLXV. Proteolytic enzymes. 15. Inhibition of guinea pig complement by derivatives of m-phenoxypropoxybenzamidine Bernard Randall Baker and Michael Cory pp 1053 - 1056; DOI: 10.1021/jm00306a020 |
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Synthesis and biological activity of some new N6-substituted purine nucleosides Maurice H. Fleysher, A. Bloch, M. T. Hakala, and C. A. Nichol pp 1056 - 1061; DOI: 10.1021/jm00306a021 |
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N.M.R. chemical shifts in carcinogenic polynuclear hydrocarbons K. D. Bartle, Derry Wynn Jones, and R. S. Matthews pp 1062 - 1065; DOI: 10.1021/jm00306a022 |
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Novel anthelmintic agents. II. Pyrantel and other cyclic amidines James W. McFarland, L. H. Conover, Harold L. Howes, J. E. Lynch, D. R. Chisholm, W. C. Austin, R. L. Cornwell, J. C. Danilewicz, W. Courtney, and D. H. Morgan pp 1066 - 1079; DOI: 10.1021/jm00306a023 |
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Novel anthelmintic agents. III. 1-(2-Arylvinyl)pyridinium salts James W. McFarland and Harold L. Howes pp 1079 - 1086; DOI: 10.1021/jm00306a024 |
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Hansch and Free-Wilson analyses of inhibitory potencies of some 1-decyl-3-carbamoylpiperidines against butyrylcholinesterase and comparison of the two methods John M. Clayton and William P. Purcell pp 1087 - 1088; DOI: 10.1021/jm00306a025 |
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3-Azaspiro[5.5]undecanes R. B. Petigara and Chimanlal V. Deliwala pp 1088 - 1089; DOI: 10.1021/jm00306a026 |
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Catechol amines. I. Sulfur analogs of norepinephrine Schneur Rachlin and Jens Enemark pp 1089 - 1092; DOI: 10.1021/jm00306a027 |
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Synthesis of some antithyroid compounds. II Pramod Kumar Srivastava and Meerasahid Saleem pp 1092 - 1093; DOI: 10.1021/jm00306a028 |
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Antiinflammatory aryl pyridyl ketones Goetz E. Hardtmann, William J. Houlihan, and E. I. Takesue pp 1093 - 1096; DOI: 10.1021/jm00306a029 |
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Synthesis of some 4-anilino-3-quinolinecarboxylic acids and esters J. William Hanifin, Rosemary Capuzzi, and Elliott Cohen pp 1096 - 1097; DOI: 10.1021/jm00306a030 |
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Heterocyclic substituted ureas. III. Immunosuppressive and antiviral (2-pyrimidinyl)ureas Charles J. Paget, Charles W. Ashbrook, Robert Louis Stone, and Donald C. DeLong pp 1097 - 1098; DOI: 10.1021/jm00306a031 |
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Anticholinergic esters of 2,6-bis(methoxymethyl)piperidin-4-ol D. G. Hill and A. B. A. Jansen pp 1101 - 1102; DOI: 10.1021/jm00306a032 |
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Preparation of substituted N-carbamoylpyrazinecarboxamides J. William Hanifin, Rosemary Capuzzi, and Elliott Cohen pp 1102 - 1103; DOI: 10.1021/jm00306a033 |
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Potential antiparkinsonism agents. Quinuclidinyl benzhydryl ethers J. Lars G. Nilsson, Jorgen Wagermark, and Richard Dahlbom pp 1103 - 1105; DOI: 10.1021/jm00306a034 |
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Alkylsulfonamido estrogens Douglas G. Mikolasek, Duane G. Gallo, Joseph L. Minielli, Gordon R. McKinney, and A. A. Larsen pp 1105 - 1106; DOI: 10.1021/jm00306a035 |
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Tests of compounds for molluskicidal activity. VI. 4-(Substituted phenoxy)-3,.beta.-dinitrostyrenes Howard W. Bond, Joseph S. O'Grodnick, and Benjamin H. Pringle pp 1107 - 1108; DOI: 10.1021/jm00306a036 |
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Antimalarials. 3,3'-Dinitro(or amino)-4,4'-di(substituted amino)diphenyl sulfones Henry Bader, John F. Hoops, John H. Biel, Harlen H. Koelling, Robert G. Stein, and Tara Singh pp 1108 - 1109; DOI: 10.1021/jm00306a037 |
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Synthesis and activity of some N-substituted .alpha.-(2-n-hexyl-4,5-dimethoxyphenyl)ethylamines against Entamoeba histolytica A. U. Dey and B. Pathak pp 1110 - 1110; DOI: 10.1021/jm00306a038 |
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A Novel Synthesis of N-dialkylaminoalkylbenzimidazoles Ned D. Heindel, John E. Orloff, and Cyrus J. Ohnmacht pp 1110 - 1111; DOI: 10.1021/jm00306a039 |
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Carcinogenic activity of analogs of p-dimethylaminoazobenzene. IX. Activity of the quinoxaline and indazole analogs Ellis Vincent Brown and William M. Fisher pp 1113 - 1114; DOI: 10.1021/jm00306a040 |
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.alpha.-Amidrazonium thiosulfates as potential antiradiation agents Tomas Lee Fridinger and Jerry Earl Robertson pp 1114 - 1115; DOI: 10.1021/jm00306a041 |
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5-Nitro-8-quinolinols and their copper(II) complexes. Implications of the fungal spore wall as a possible barrier against potential antifungal agents Herman Gershon, Maynard W. McNeil, and Yvonne J. Hinds pp 1115 - 1117; DOI: 10.1021/jm00306a042 |
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6,6'-Dithiobispurinyl nucleosides Fred Keller and James E. Bunker pp 1117 - 1118; DOI: 10.1021/jm00306a043 |
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Synthesis and evaluation of salts of ethylene-maleic acid copolymers as antitumor agents Ernest M. Hodnett, Neil Purdie, William J. Dunn, and John S. Harger pp 1118 - 1120; DOI: 10.1021/jm00306a044 |
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Synthesis of 3-hydroxy- and 3-methoxyindole-2-carboxamides and esters Mahendra P. Saxena and Shakti R. Ahmed pp 1120 - 1121; DOI: 10.1021/jm00306a045 |
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Pyrimido[4,5-e][1,4] diazepin-5-ones and 4,4-ethylenediaminobis(2-phenyl-pyrimidine-5-carboxylic acid) diethyl esters Dong Han Kim and Arthur A. Santilli pp 1121 - 1122; DOI: 10.1021/jm00306a046 |
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Potential antineoplastics. I. 2-Amino-4,6-dimethyl-5-arylazopyrimidines and 1-thiocarbamoyl-3,5-diphenyl-4-arylazopyrazoles Hari G. Garg and Ram Ashrey Sharma pp 1122 - 1124; DOI: 10.1021/jm00306a047 |
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Iodine derivatives of dibenamine Herbert Alter Friedman and George B. Koelle pp 1124 - 1124; DOI: 10.1021/jm00306a048 |
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1-Methyl-4-[5(3)-methyl-3(5)-pyrazolyl]quinolinium iodide. An analog of the hypoglycemic pyrazolylpyridinium salts Richard P. Williams, Victor J. Bauer, and Sidney R. Safir pp 1124 - 1125; DOI: 10.1021/jm00306a049 |
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9-(2,3,4-tri-O-benzyl-D-arabinopyranosyl)Purines Abelardo P. Martinez, William Wei Lee, and Leon Goodman pp 1125 - 1125; DOI: 10.1021/jm00306a050 |
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Muscle Relaxant and Anticonvulsant Properties of Some 1-Carbamoyl-3-aroylpyrrolidines and 1-Carbamoyl-4-aroylpiperidines Grover C. Helsley, Robert L. Duncan, Jr, and William H. Funderburk pp 1098 - 1100; DOI: 10.1021/jm00306a600 |
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Book Reveiws pp 1126 - 1126; DOI: 10.1021/jm00306a601 |
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Additions and Corrections - Hycanthone, a New Active Metabolite of Lucanthone. D. Rosi, G. Peruzzotti, E. W. Dennis, D. A. Berberian, H. Freele, B. F. Tullar, and S. Archer pp 1127 - 1127; DOI: 10.1021/jm00306a602 |
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Additions and Corrections - Irreversible Enzyme Inhibitors. CXIII. Proteolytic Enzymes. III. Active-Site-Directed Irreversible Inhibitors of α-Chymotrypsin Derived from Phenoxyacetamides with an N-Fluorosulfonylphenyl Substituent. B. R .Baker, and Jeffrey A. Hurlbut pp 1127 - 1127; DOI: 10.1021/jm00306a603 |
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Additions and Corrections - Potential Antihypertensive Agents . II. Unsymmetrically 1,4-Disubstituted Piperazines. I. Raj Nandan Prasad, Leslie R. Hawkins, and Karen Tieje pp 1127 - 1127; DOI: 10.1021/jm00306a604 |
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Additions and Corrections - Sulfonylureas Having Diuretic Activity Bernard Loev, and Kenneth M. Snader pp 1127 - 1127; DOI: 10.1021/jm00306a605 |
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Additions and Corrections - Antimalarial Activity of Guanylhydrazone Salts of Aromatic Ketones. I. Primary Search for Active Substituent Patterns. Jefferson R. DoAmaral, Erwin J. Blanz, Jr., and Frederic A. French pp 1127 - 1127; DOI: 10.1021/jm00306a606 |
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Additions and Corrections - An Analysis of Biological Linear Free-Energy Relationships A. Cammarata pp 1127 - 1127; DOI: 10.1021/jm00306a607 |
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Additions and Corrections - The Synthesis and Pharmacological Properties of a Series of 2-Sunstituted Amino-methyl-1,4-benzodioxanes. P. N. Green, M. Shapero, and C. Wilson pp 1127 - 1127; DOI: 10.1021/jm00306a608 |
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Additions and Corrections - Correlation of Biological Activity with Chemical Structure. Use of Molar Attraction Constants. James A. Ostrenga pp 1127 - 1128; DOI: 10.1021/jm00306a609 |
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Additions and Corrections - Superdelocalizability and Charge Densitiy. A Correlation with Partition Coefficients. K. S. Rogers, and A. Cammarata pp 1128 - 1128; DOI: 10.1021/jm00306a610 |
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Additions and Corrections - Antiamebic, Antimalarial, and Antihelmintic Effects of Distal Hydrazine Analogs of Azacrine, Quinnacrine, and 7-{[3-(Octylamino)propyl]amino}benzyl[c]acridine Edward F. Elslager, and Donald F. Worth pp 1128 - 1128; DOI: 10.1021/jm00306a611 |
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The Synthesis and Antitrichomonad Activity of 2-Substituted 4,8-Dithiaspiro[2.5]octanes (Dithianes) J.P. O'Brien, A.I. Rachlin, and S. Teitel pp 1112 - 1112; DOI: 10.1021/jm00306a900 |